Black Slime is a toxic and dangerous substance filled with concentrated negative energy and it is from Ghostbusters: The Video Game (Realistic Versions), and in Ghostbusters: The Video Game (Stylized Versions).
According to Tobin's Spirit GuideEdit
- Class 1 Caustic Seep
- Environmental (inert)
Black Slime is encountered in locations of intersection between the real and ghost worlds. It is a dangerous substance formed of ectoplasm supersaturated with negative energy. Black Slime is incredibly caustic and will cause severe damage to anyone heedless enough to come into contact with it.
Based on its spectral resonance echo, Black Slime also appears to function as a conduit for PKE energy and could, if saturated with enough spiritual energy, conceivably act as a ghost portal.
Contact protocol for this caustic substance is to not make contact at all! Even minimal contact can cause moderate damage-and that's with protective gear in place. Avoid this substance at all costs and neutralize with positively charged slime from your Slime Blower whenever possible.
Black Slime is a substance found in locations of intersection between the "real" world and the "ghost" world. Black Slime can be completely neutralized by the positively charged Psychomagnotheric Slime that is used by Ghostbusters.
Black Slime in its initial state is an extremely dangerous substance that is formed of Ectoplasm and is supersaturated with negative energy. It is incredibly caustic and will cause damage to both the body and soul of anyone heedless enough to come into contact with it. Black Slime is usually very rare, however.
It is first encountered by the Rookie in the Sedgewick Hotel, in the kitchen. When encountered in front of the theater, on the Times Square, Ray Stantz warned that the slime is very dangerous and that he and Egon Spengler have not been able to develop uniforms and boots to counteract its deadly nature. Contrary to the Mood Slime encountered during the Vigo Incident, the slime is not used to channel negative energy to a human host.
The Cult's Black SlimeEdit
The Cult of Gozer under the leadership of Ivo Shandor, was able to capture a Sloar which proved to be nearly limitless source of this usually rare, slimy resource. This mass-produced Black Slime was used to create Psychomagnotheric Slime, which filled New York's underground tunnels. However, the Cult also found other uses for the Black Slime.
The Black Slime was used by the Cult's members to empower themselves magically, allowing them to create such things as Mandalas and properly operate them. Large amounts of Black Slime were placed in each of Mandala's locations. Ivo Shandor and his fellow cultists discovered that the Black Slime, in big amounts, could be used to create rifts for ghosts to enter our world. As the Cult's important places (which Ghostbusters later visit in 1991) were filled with this slime, the ghosts were feeling themselves very comfortable to manifest in big amounts.
The slime was also the tool that granted the Cult members eternal life: many of the cultists manifested in the form of Black Slime creatures, while the most powerful of them, like The Chairman, Azetlor the Destroyer and Spider Witch, were able to use it to boost themselves into powerful "supreme deities", still dependent, though, on the slime, as their power were directly connected to a Mandala's functioning.
Black Slime CreaturesEdit
While many of the most powerful Cult members were able to manifest in their ghost forms without the help of the Black Slime, other were "bound" to it and reappeared in the forms of minions entirely or partially composed of slime.
- Black Slime Fiend
- Black Slime Ghost
- Black Slime Monster
- Black Slime Behemoth (Stylized version only)
- Several members of the Terminal Reality development team provided the voices of the Black Slime. 
- On page 23 of Ghostbusters Issue #5, Black Slime is referred to in the Sam Hain PCOC file.
- Psychomagnotheric Slime
- Not to be confused with the Black Slime. This slime was created from the Black Slime by Ivo Shandor and have absolutely different characteristics.
- The term that describes all ghostly activity.