George Washington Bridge is a bridge connecting Washington Heights, Manhattan to Fort Lee, New Jersey across the Hudson River.
In November 1997, four Ecto-Clones manifested and attacked the George Washington Bridge. They ate up vehicles and the bridge's steel cables. The original Ghostbusters arrived and tried to stall them with car parts to the motorists could evacuate off the bridge. The stability of the bridge was jeopardized by the entity's eating. The Extreme Ghostbusters arrived on the scene, trapped the entities, and saved their predecessors from certain death.