The Museum of Crime  is an institution located in Uptown that owns collections of artifacts from various eras and cultures related to great crimes and criminals.
In a bid to solidify himself, James Moriarty was led to the Museum of Crime by the Hound of the Baskervilles. After patrons vacated the museum, Moriarty absorbed the evil from various objects and grew stronger. The Ghostbusters tried to engage the ghosts but their Particle Throwers had no effect on them. As Moriarty was about to kill them, the Ghostbusters were saved by John H. Watson. After Moriarty and the Hound left the museum, Peter Venkman trapped Sherlock Holmes.
- ↑ Janine Melnitz (2009). The Real Ghostbusters - "Elementary My Dear Winston" (1989) (DVD ts. 08:34-08:36). Time Life Entertainment. Janine says: "Uptown! Museum of Crime!"