"The prime motivator is a demon named W(h)at."
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The Pursuing Spider follow the Ghostbusters in Scene 1: Tunnel of Slime, Scene 3: Order in the Court, Scene 5: Subway Slime, and Scene 7: Storming the Museum of Ghostbusters II Video Game.
They follow the player til the end of the scene and can not be trapped or slimed. They attack the Ghostbuster if they catch up.